Lindon Young, PhD - Publications
Protein kinase C (PKC) isoform peptide activator/inhibitors exert cardioprotective effects in polymorphonuclear leukocyte (PMN)-induced ischemia/reperfusion (I/R) injury. Young LH, Phillipson A, Omiyi D, Atkinson N, Jivani M, Adams J, Peterman EE, Taormina PII, Brue RJ and Harvey M. 2006. Understanding Biology Using Peptides, Proceedings of the 19th American Peptide Symposium SE Blondelle, Editor 457-458.
Go 6983: A fast acting protein kinase C inhibitor that attenuates myocardial ischemia/reperfusion injury. Young, L.H., B. J. Balin, and M. T. Weis. 2005. Cardiovascular Drug Reviews 23: 255-272.
Protein kinase C beta II (PKC-βII) peptide inhibitor exerts cardioprotection in polymorphonuclear leukocyte (PMNs) induced ischemia/reperfusion (I/R) injury. Omiyi D, Brue R, Taormina P, Harvey M, Atkinson NK and Young, LH. 2005. J Pharmacol Exp Thera 314: 542-551.
Protein kinase C zeta inhibition exerts cardioprotective effects in ischemia/reperfusion injury. Phillipson A., E. E. Peterman, P. Taormina II, M. Harvey, R. J. Brue, N. Atkinson, D. Omiyi, U. Chukwu, and L. H. Young. 2005. Am. J. Physiol. 289:H898-907.
Go 6983 exerts cardioprotective effects in myocardial ischemia/reperfusion. Peterman, E. E., P. Taormina II, M. Harvey, and L. H. Young. 2004. J. Cardiovasc. Pharmacol. 43: 645-656.
Inhibiting long chain fatty Acyl CoA synthetase increases basal and agonist-stimulated NO synthesis in endothelium. Weis, M. T., J. L. Crumley, L. H. Young, and J. N. Stallone. 2004. Cardiovasc. Res. 63:338-346.
Rosuvastatin, a new HMG-CoA reductase inhibitor, protects ischemic reperfused myocardium in normocholesterolemic rats. Ikeda, Y., L. H. Young, and A. M. Lefer. 2003. J. Cardiovasc. Pharmacol. 41:649-656.
Attenuation of neutrophil-mediated myocardial ischemia-reperfusion injury by a calpain inhibitor. Ikeda, Y., L. H. Young, and A. M. Lefer. 2002. Am. J. Physiol. Heart Circ. Physiol. 282:H1421-6.
Vascular effects of poly-N-acetylglucosamine in isolated rat aortic rings. Ikeda, Y., L. H. Young, J. N. Vournakis, and A. M. Lefer. 2002. J. Surg. Res. 102:215-220.
Mg2+ efflux from the isolated perfused rabbit heart is mediated by two states of the beta1-adrenergic receptor. Young, L., A. Bercute-Dammann, and M. T. Weis. 2002. Naunyn Schmiedebergs Arch. Pharmacol. 366:431-439.
Protein kinase inhibition exerts cardioprotective effects in myocardial ischemia/reperfusion via inhibition of superoxide release. Young, L. H., Y. Ikeda, and A. M. Lefer. 2001. Methods Find. Exp. Clin. Pharmacol. 23:107-114.
Caveolin-1 peptide exerts cardioprotective effects in myocardial ischemia-reperfusion via nitric oxide mechanism. Young, L. H., Y. Ikeda, and A. M. Lefer. 2001. Am. J. Physiol. Heart Circ. Physiol. 280:H2489-95.
PR-39, a proline/arginine-rich antimicrobial peptide, exerts cardioprotective effects in myocardial ischemia reperfusion. Ikeda, Y., L. H. Young, R. Scalia, C. R. Ross, and A. M. Lefer. 2001. Cardiovasc. Res. 49:69-77.
Cardioprotective effects of citrulline in ischemia/reperfusion injury via a non-nitric oxide-mediated mechanism. Ikeda, Y., L. H. Young, R. Scalia, and A. M. Lefer. 2000. Methods Find. Exp. Clin. Pharmacol. 22:563-571.
Wortmannin, a potent antineutrophil agent, exerts cardioprotective effects in myocardial ischemia/reperfusion. Young, L. H., Y. Ikeda, R. Scalia, and A. M. Lefer. 2000. J. Pharmacol. Exp. Ther. 295:37-43.
C-peptide exerts cardioprotective effects in myocardial ischemia-reperfusion. Young, L. H., Y. Ikeda, R. Scalia, and A. M. Lefer. 2000. Am. J. Physiol. Heart Circ. Physiol. 279:H1453-9.
Expression of a vitamin D-regulated gene (VDUP-1) in untreated- and MNU-treated rat mammary tissue. Yang, X., L. H. Young, and J. M. Voigt. 1998. Breast Cancer Res. Treat. 48:33-44.